Use Caution/Monitor. They may recommend that you stop taking candesartan until you're better and you're able to eat and drink normally again. hydrochlorothiazide and gentamicin both decrease serum potassium. Thiazide dosage >50 mg/day may increase blood glucose. Either increases toxicity of the other by pharmacodynamic synergism. Monitor Closely (1)hydrochlorothiazide will increase the level or effect of probenecid by acidic (anionic) drug competition for renal tubular clearance. Use Caution/Monitor. ChildrenUse and dose must be determined by your doctor. Use Caution/Monitor.acemetacin increases and hydrochlorothiazide decreases serum potassium. Modify Therapy/Monitor Closely.candesartan and drospirenone both increase serum potassium. Either increases effects of the other by pharmacodynamic synergism. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Use Caution/Monitor. Monitor Closely (1)hydrochlorothiazide and deflazacort both decrease serum potassium. Select one or more newsletters to continue. Either increases effects of the other by pharmacodynamic synergism. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. hydrochlorothiazide decreases effects of insulin lispro by pharmacodynamic antagonism. amifostine, hydrochlorothiazide. Adult. Minor/Significance Unknown. Modify Therapy/Monitor Closely. Your blood pressure may decrease during the first 2 weeks of your treatment, but it may take 4 to 6 weeks for you to notice the full benefit of candesartan. Monitor patients for changes in glycemic control. candesartan and diclofenac both increase serum potassium. Effect of interaction is not clear, use caution. Comment: Potential for increased risk of hypotension with concurrent use. Use Caution/Monitor. Risk of fetal compromise if given during pregnancy. Either increases effects of the other by pharmacodynamic synergism. Mechanism: pharmacodynamic synergism. Effect of interaction is not clear, use caution. Mechanism: pharmacodynamic synergism. hydrochlorothiazide decreases effects of insulin NPH by pharmacodynamic antagonism. Monitor Closely (1)candesartan increases effects of insulin detemir by unspecified interaction mechanism. Either increases toxicity of the other by Other (see comment). Minor (1)hydrochlorothiazide increases levels of calcium acetate by decreasing renal clearance. Monitor Closely (3)candesartan and nadolol both increase serum potassium. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. Minor (1)calcitriol topical, hydrochlorothiazide. hydrochlorothiazide, toremifene. Use Caution/Monitor. Either increases levels of the other by decreasing renal clearance. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. Minor/Significance Unknown. Thiazide dosage >50 mg/day may increase blood glucose. Minor/Significance Unknown. Monitor Closely (2)hydrochlorothiazide decreases effects of liraglutide by pharmacodynamic antagonism. Effect of interaction is not clear, use caution. Applies to the following strengths: 16 mg-12.5 mg; 32 mg-12.5 mg; 32 mg-25 mg. Candesartan 16 to 32 mg-Hydrochlorothiazide 12.5 to 50 mg orally daily in 1 to 2 divided doses Comment: Angiotensin II receptor antagonists may enhance hypoglycemic effects of antidiabetic agents by improving insulin sensitivity. Opioids can reduce diuretic efficacy by inducing antidiuretic hormone release. celecoxib decreases effects of candesartan by pharmacodynamic antagonism. Minor/Significance Unknown. Avoid or Use Alternate Drug. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. hydrochlorothiazide decreases effects of nateglinide by pharmacodynamic antagonism. Monitor Closely (1)fentanyl intranasal decreases effects of hydrochlorothiazide by Other (see comment). Use Caution/Monitor. Use Caution/Monitor. Candesartan drug Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.oxaprozin decreases effects of candesartan by pharmacodynamic antagonism. Mechanism: pharmacodynamic synergism. drospirenone increases and hydrochlorothiazide decreases serum potassium. Use Caution/Monitor. Copyright: Merative US L.P. 1973, 2023. candesartan increases and torsemide decreases serum potassium. Use Caution/Monitor. Use Caution/Monitor. Monitor congestive heart failure patients closely for the first 2 weeks of treatment with this drug and following a dose increase of candesartan or a diuretic. Use Caution/Monitor. Use Caution/Monitor. Candesartan comes as a tablet to take by mouth. Monitor Closely (1)ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) will increase the level or effect of candesartan by unspecified interaction mechanism. hydrochlorothiazide will increase the level or effect of acemetacin by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown. maitake increases effects of hydrochlorothiazide by pharmacodynamic synergism. Modify Therapy/Monitor Closely. Either increases toxicity of the other by Other (see comment). Minor/Significance Unknown. Mechanism: pharmacodynamic synergism. Risk of alkalosis, hypercalcemia. Monitor Closely (1)telmisartan increases and hydrochlorothiazide decreases serum potassium. Increased risk of systemic hyponatremia. Minor/Significance Unknown. Use Caution/Monitor. Consider decreasing dosage of antihypertensive agent. Hypokalemia. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. Minor/Significance Unknown. The usual dose ranges from 8 to 32 mg/day. Minor/Significance Unknown. candesartan increases effects of insulin degludec by unspecified interaction mechanism. Use Caution/Monitor. Monitor patients for changes in glycemic control. candesartan, diclofenac. hydrochlorothiazide, sulfamethoxazole. Do not stop taking candesartan without talking to your doctor. Minor/Significance Unknown. Monitor Closely (4)tolmetin decreases effects of candesartan by pharmacodynamic antagonism. Controlled studies in pregnant women show no evidence of fetal risk. Minor/Significance Unknown. Use Caution/Monitor. Monitor Closely (3)carvedilol, candesartan. Use Caution/Monitor. reishi increases effects of hydrochlorothiazide by pharmacodynamic synergism. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Mechanism: pharmacodynamic synergism. fenoprofen decreases effects of candesartan by pharmacodynamic antagonism. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Usual Adult Dose for Hypertension. Effect of interaction is not clear, use caution. Use Caution/Monitor. candesartan increases effects of exenatide injectable suspension by Other (see comment). candesartan and celecoxib both increase serum potassium. Minor/Significance Unknown. methylphenidate transdermal decreases effects of hydrochlorothiazide by anti-hypertensive channel blocking. Either increases toxicity of the other by pharmacodynamic synergism. Starting Dose. Information is also available online at https://www.poisonhelp.org/help. Use Caution/Monitor. Modify Therapy/Monitor Closely. Fentanyl may also lead to acute urinary retention by causing bladder sphincter spasm (particularly in men with enlarged prostates). Monitor BP. Use Caution/Monitor. Monitor Closely (2)candesartan increases and furosemide decreases serum potassium. Use Caution/Monitor. candesartan, captopril. Use Caution/Monitor. Monitor Closely (1)fentanyl transmucosal decreases effects of hydrochlorothiazide by Other (see comment). Candesartan cilexetil | Drugs | BNF | NICE High blood pressure often has no symptoms. Effect of interaction is not clear, use caution. Use Caution/Monitor. Candesartan is also sometimes used to treat diabetic nephropathy (kidney disease in people with diabetes and high blood pressure). Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Minor/Significance Unknown. candesartan increases effects of insulin glargine by unspecified interaction mechanism. Thiazide dosage >50 mg/day may increase blood glucose. Comment: Diuretics may cause hyperglycemia and glycosuria in patients with diabetes mellitus, possibly by diuretic-induced hpokalemia. hydrochlorothiazide decreases effects of insulin degludec/insulin aspart by Other (see comment). Use Caution/Monitor.Minor (1)ephedrine, hydrochlorothiazide. chlorthalidone will increase the level or effect of hydrochlorothiazide by acidic (anionic) drug competition for renal tubular clearance. choline magnesium trisalicylate decreases effects of candesartan by pharmacodynamic antagonism. Use Caution/Monitor.Minor (1)epinephrine racemic, hydrochlorothiazide. Use Caution/Monitor. hydrochlorothiazide increases effects of minoxidil by pharmacodynamic synergism. Use Caution/Monitor.Minor (1)hydrochlorothiazide increases levels of penicillin G aqueous by decreasing renal clearance. Monitor Closely (1)candesartan and fenbufen both increase serum potassium. Mechanism: pharmacodynamic synergism. Avoid or Use Alternate Drug. carbamazepine, hydrochlorothiazide. candesartan and propranolol both increase serum potassium. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect.candesartan, naproxen. Use Caution/Monitor. Use Caution/Monitor. bisoprolol, candesartan. Coadministration with drugs associated with nephrotoxicity may increase the risk for acute and/or chronic nephrotoxicity. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. . salsalate decreases effects of candesartan by pharmacodynamic antagonism. atenolol, candesartan. Modify Therapy/Monitor Closely. Either increases effects of the other by pharmacodynamic synergism. nitroglycerin rectal, candesartan. Use Caution/Monitor. Risk of alkalosis, hypercalcemia. Use Caution/Monitor. Effect of interaction is not clear, use caution. Use Caution/Monitor. Effect of interaction is not clear, use caution. What Are Dosages of Candesartan? Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. hydrochlorothiazide will increase the level or effect of ibuprofen by acidic (anionic) drug competition for renal tubular clearance. Medication Guide Drug Description Find Lowest Prices on What is Atacand and how is it used? Risk of hypokalemia, especially with strong glucocorticoid activity. Minor/Significance Unknown. AHFS Patient Medication Information. Minor/Significance Unknown. Use Caution/Monitor.Minor (1)hydrochlorothiazide will increase the level or effect of fenbufen by acidic (anionic) drug competition for renal tubular clearance. Monitor blood pressure and renal function.Serious - Use Alternative (1)candesartan, captopril. Modify Therapy/Monitor Closely. candesartan increases and methyclothiazide decreases serum potassium. candesartan, meclofenamate. Either increases effects of the other by pharmacodynamic synergism. Atacand is also used in adults to treat certain types of heart failure and lower your risk of death or needing to be hospitalized for heart damage. Thiazide dosage >50 mg/day may increase blood glucose. Minor/Significance Unknown. Monitor Closely (4)candesartan and aspirin both increase serum potassium. Use Caution/Monitor. candesartan, ketoprofen. Possible additive hyponatremia. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect.Minor (1)hydrochlorothiazide will increase the level or effect of mefenamic acid by acidic (anionic) drug competition for renal tubular clearance. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. May enhance hypokalemic effect of thiazide diuretics. Concomitant use of insulin and ARBs may require insulin dosage adjustment and increased glucose monitoring. Concomitant use of insulin and ARBs may require insulin dosage adjustment and increased glucose monitoring. Use Caution/Monitor. Risk of fetal compromise if given during pregnancy.candesartan and bisoprolol both increase serum potassium. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. Thiazide dosage >50 mg/day may increase blood glucose. Monitor Closely (2)candesartan increases effects of albiglutide by Other (see comment). Concomitant use of insulin and ARBs may require insulin dosage adjustment and increased glucose monitoring.Minor (1)hydrochlorothiazide decreases effects of insulin regular human by pharmacodynamic antagonism. Minor/Significance Unknown. Avoid or Use Alternate Drug. Modify Therapy/Monitor Closely. Effect of interaction is not clear, use caution. Comment: Coadministration with medications that cause fluid and electrolyte abnormalities may increase the risk of adverse events of seizure, arrhythmias, and renal impairment. Do not let anyone else take your medication. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect. Monitor Closely (1)arformoterol and hydrochlorothiazide both decrease serum potassium. Initial dose: 16 mg orally once a day epinephrine and hydrochlorothiazide both decrease serum potassium. Monitor Closely (4)candesartan and sulfasalazine both increase serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely. cholestyramine decreases levels of hydrochlorothiazide by inhibition of GI absorption. Modify Therapy/Monitor Closely. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect. Either increases effects of the other by pharmacodynamic synergism. If you become pregnant while you are taking candesartan, stop taking candesartan and call your doctor immediately. Effect of interaction is not clear, use caution. cyclosporine increases toxicity of hydrochlorothiazide by unspecified interaction mechanism. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Minor/Significance Unknown. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.etodolac decreases effects of candesartan by pharmacodynamic antagonism. Minor/Significance Unknown. Use Caution/Monitor. Use Caution/Monitor. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Either increases toxicity of the other by pharmacodynamic synergism. candesartan and aceclofenac both increase serum potassium. When amifostine is used at chemotherapeutic doses, withhold blood pressure lowering medications for 24 hr prior to amifostine; if blood pressure lowering medication cannot be withheld, do not administer amifostine. Effect of interaction is not clear, use caution. Use Caution/Monitor.acebutolol, candesartan. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.ketorolac increases and hydrochlorothiazide decreases serum potassium. Monitor Closely (1)hydrochlorothiazide, shark cartilage. Concomitant use of insulin and ARBs may require insulin dosage adjustment and increased glucose monitoring. Use Caution/Monitor. Take the candesartan packet, or the leaflet inside it, plus any remaining medicine with you. candesartan and tolvaptan both increase serum potassium. Risk of hypokalemia, especially with strong glucocorticoid activity. Possible additive hyponatremia. Use Caution/Monitor. Thiazide dosage >50 mg/day may increase blood glucose. Avoid or Use Alternate Drug. Minor/Significance Unknown. Monitor Closely (4)ketoprofen decreases effects of candesartan by pharmacodynamic antagonism. Modify Therapy/Monitor Closely. candesartan, mefenamic acid. Comment: Juniper may potentiate or interfere with diuretic therapy. Risk of prolonged QTc interval. In people with liver or kidney problems, the dose may be lower. Avoid or Use Alternate Drug. Use Caution/Monitor.Minor (1)brimonidine increases effects of hydrochlorothiazide by pharmacodynamic synergism. Candesartan / Hydrochlorothiazide Dosage - Drugs.com oliceridine decreases effects of hydrochlorothiazide by Other (see comment). Use Caution/Monitor.Serious - Use Alternative (1)hydrochlorothiazide increases levels of dofetilide by decreasing renal clearance. Mechanism: pharmacodynamic synergism. Risk of hypotension.Minor (1)tizanidine increases effects of hydrochlorothiazide by pharmacodynamic synergism. Thiazide diuretics can decrease insulin sensitivity thereby leading to glucose intolerance and hyperglycemia. . Medically reviewed by Drugs.com. Candesartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. candesartan, ibuprofen. Monitor Closely (1)empagliflozin, hydrochlorothiazide. Either increases toxicity of the other by pharmacodynamic synergism. candesartan and ibuprofen both increase serum potassium. Either increases effects of the other by pharmacodynamic synergism. Last updated on Jan 31, 2023. Take candesartan even if you feel well, as you will still be getting the benefits of the medicine. Comment: Coadministration with medications that cause fluid and electrolyte abnormalities may increase the risk of adverse events of seizure, arrhythmias, and renal impairment.sodium sulfate/?magnesium sulfate/potassium chloride increases toxicity of hydrochlorothiazide by Other (see comment). Monitor Closely (3)betaxolol, candesartan. Mechanism: pharmacodynamic synergism. succinylcholine increases and hydrochlorothiazide decreases serum potassium. albuterol and hydrochlorothiazide both decrease serum potassium. Either increases effects of the other by pharmacodynamic synergism. Minor/Significance Unknown. Monitor Closely (1)hydrochlorothiazide decreases levels of trientine by increasing renal clearance. Candesartan candesartan and sacubitril/valsartan both increase serum potassium. Comment: Thiazide diuretics may increase serum calcium by decreasing urinary calcium excretion. We comply with the HONcode standard for trustworthy health information. Modify Therapy/Monitor Closely. Avoid or Use Alternate Drug. Minor (1)hydrochlorothiazide decreases effects of tolbutamide by pharmacodynamic antagonism. Minor/Significance Unknown. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Minor/Significance Unknown. Use Caution/Monitor.celecoxib decreases effects of candesartan by pharmacodynamic antagonism. Mayo Clinic does not endorse companies or products. Comment: Angiotensin II receptor antagonists may enhance hypoglycemic effects of antidiabetic agents by improving insulin sensitivity. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect.tolmetin increases and hydrochlorothiazide decreases serum potassium. Effect of interaction is not clear, use caution. Minor (1)cosyntropin, hydrochlorothiazide. Use Caution/Monitor. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect.ketoprofen increases and hydrochlorothiazide decreases serum potassium. meclofenamate increases and hydrochlorothiazide decreases serum potassium. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect. -For children unable to swallow tablets, an extemporaneously compounded suspension may be used instead. Effect of interaction is not clear, use caution. Mechanism: pharmacodynamic synergism. Hypokalemia.hydrochlorothiazide decreases effects of norepinephrine by pharmacodynamic antagonism. Use Caution/Monitor. Effect of interaction is not clear, use caution. WebATACAND (candesartan cilexetil) tablets, for oral *. Possible enhanced electrolyte loss. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Atacand only for the indication prescribed. Minor (1)hydrochlorothiazide decreases effects of tolazamide by pharmacodynamic antagonism. Modify Therapy/Monitor Closely. potassium chloride increases and hydrochlorothiazide decreases serum potassium. Effect of interaction is not clear, use caution. ibuprofen IV decreases effects of candesartan by pharmacodynamic antagonism. Risk of hypokalemia, especially with strong glucocorticoid activity. hydrochlorothiazide and sodium sulfate/potassium chloride/magnesium sulfate/polyethylene glycol both decrease serum potassium. Use Caution/Monitor. Use Caution/Monitor.Minor (1)hydrochlorothiazide, carbenoxolone. Serious - Use Alternative (2)lofexidine, hydrochlorothiazide. candesartan increases and terbutaline decreases serum potassium. Mechanism: pharmacodynamic synergism. diclofenac increases and hydrochlorothiazide decreases serum potassium. Monitor Closely (2)candesartan and acemetacin both increase serum potassium. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Comment: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. Use Caution/Monitor. Avoid administering other phototoxic drugs with aminolevulinic acid oral for 24 hr during perioperative period. This drug is available at a higher level co-pay. Minor/Significance Unknown. Atacand: Drug Facts, Dosage & Side Effects - Drugs.com Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Either increases levels of the other by decreasing renal clearance. Atacand: 16 mg [scored; contains corn starch] Atacand: 32 mg [DSC] [scored] Atacand: 32 mg [scored; contains corn starch] Generic: 4 mg, 8 mg, 16 mg, 32 mg celiprolol, candesartan. Effect of interaction is not clear, use caution. Effect of interaction is not clear, use caution. cefamandole will increase the level or effect of hydrochlorothiazide by acidic (anionic) drug competition for renal tubular clearance. hydrochlorothiazide and carbenoxolone both decrease serum potassium. Use Caution/Monitor. candesartan and ketoprofen both increase serum potassium. Your blood pressure should be checked regularly to determine your response to candesartan. Hypokalemia. bitter melon, hydrochlorothiazide. Monitor Closely (1)losartan increases and hydrochlorothiazide decreases serum potassium. This content does not have an Arabic version. Comment: Coadministration with medications that cause fluid and electrolyte abnormalities may increase the risk of adverse events of seizure, arrhythmias, and renal impairment. Minor (1)hydrochlorothiazide decreases levels of magnesium citrate by increasing renal clearance. tizanidine increases effects of candesartan by pharmacodynamic synergism. Monitor Closely (1)candesartan, eplerenone. Use Caution/Monitor. Monitor Closely (1)umeclidinium bromide/vilanterol inhaled and hydrochlorothiazide both decrease serum potassium. Administration advice: Administer with or without food. Comment: Low molecular weight heparins may suppress adrenal aldosterone secretion, which can potentially cause hyperkalemia. Minor/Significance Unknown. Use Caution/Monitor. Thiazide dosage >50 mg/day may increase blood glucose. Monitor Closely (3)bisoprolol increases and hydrochlorothiazide decreases serum potassium. Trimethoprim decreases urinary potassium excretion. For adults with severe kidney problems: A starting dose of 8 mg or less per day. Minor (2)shepherd's purse, candesartan. esmolol increases and hydrochlorothiazide decreases serum potassium. candesartan and labetalol both increase serum potassium. Use Caution/Monitor. Effect of interaction is not clear, use caution. candesartan, quinapril. Monitor Closely (2)candesartan increases effects of exenatide injectable suspension by Other (see comment). Use Caution/Monitor. tadalafil increases effects of candesartan by pharmacodynamic synergism. Minor/Significance Unknown. hydrochlorothiazide increases effects of digoxin by pharmacodynamic synergism. beclomethasone, inhaled increases toxicity of hydrochlorothiazide by increasing elimination. Use Caution/Monitor. candesartan, aspirin. Use Caution/Monitor. Minor/Significance Unknown. Mechanism: pharmacodynamic synergism. Monitor Closely (1)maraviroc, candesartan. hydrochlorothiazide decreases effects of insulin aspart by pharmacodynamic antagonism. hydrochlorothiazide will increase the level or effect of quinine by basic (cationic) drug competition for renal tubular clearance. Use Caution/Monitor. Your doctor may occasionally change your dose. Minor/Significance Unknown. Minor (1)hydrochlorothiazide increases levels of sulfadiazine by unspecified interaction mechanism. hydrochlorothiazide will increase the level or effect of ofloxacin by basic (cationic) drug competition for renal tubular clearance. Minor/Significance Unknown. Minor/Significance Unknown. Hypokalemia increases digoxin effects.digoxin increases and hydrochlorothiazide decreases serum potassium. Monitor blood pressure and adjust dose of antihypertensive agent as needed. Effect of interaction is not clear, use caution. sotalol, candesartan. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. Either increases effects of the other by pharmacodynamic synergism. Minor/Significance Unknown. You may need to stop for a short time. Minor/Significance Unknown. etodolac decreases effects of candesartan by pharmacodynamic antagonism. Risk of fetal compromise if given during pregnancy. Use Caution/Monitor. WebThe typical dose of Candesartan is 8 mg/day (for high blood pressure). Monitor Closely (1)penicillin G aqueous, hydrochlorothiazide. agrimony increases effects of hydrochlorothiazide by pharmacodynamic synergism. High blood pressure is a common condition, and when not treated it can cause damage to the brain, heart, blood vessels, kidneys, and other parts of the body. Either increases toxicity of the other by Other (see comment). Comment: Potential for increased risk of hypotension with concurrent use. terbutaline, hydrochlorothiazide. Minor (1)hydrochlorothiazide increases levels of piperacillin by decreasing renal clearance. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. Effect of interaction is not clear, use caution. Either increases levels of the other by decreasing renal clearance. Either increases toxicity of the other by Other (see comment). Modify Therapy/Monitor Closely. Effect of interaction is not clear, use caution. Use Caution/Monitor. Use Caution/Monitor. Risk of hypotension. Use Caution/Monitor. Minor/Significance Unknown. goldenrod increases effects of hydrochlorothiazide by pharmacodynamic synergism. enoxaparin increases toxicity of candesartan by Other (see comment). Minor (1)hydrochlorothiazide will increase the level or effect of mesalamine by acidic (anionic) drug competition for renal tubular clearance. Use Caution/Monitor. If you miss a dose of candesartan, take it as soon as you remember. Monitor Closely (1)fentanyl transdermal decreases effects of hydrochlorothiazide by Other (see comment).
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